Lycopodium clavatum or locally known as “lumot” is one of the many plants used in the traditional system of medicine here in the Philippines. It has been known that this plant was used for body pains and “facial wipes” recognizing its anti-aging potential by the Obo community in Lake Sebu, South Cotabato. However, there is a lack of sufficient data on its phytochemical components and medicinal properties. Thus, this study is conducted to determine the secondary metabolites present and its antioxidant property of the decoction and ethanolic extracts of Lycopodium clavatum Linn. Free radical scavenging activity of Lycopodium clavatum Linn. was determined by in vitro 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method. Antioxidant activities were observed which may be due to the presence of alkaloids, steroids, and flavonoids in both decoction and ethanolic extracts.

1.
Bai
,
D.
(
1993
).
Traditional Chinese Medicines and New Drug Development
.
Pure and Applied Chemistry.
65
1103
1112
.
2.
Hiroshi
M
,
Hirasawa
Y
,
Kobayashi
J.
(
2009
).
HETEROCYCLES: the Lycopodium Alkaloids.
77
920
,
679
.
3.
Coffey
T.
(
1993
).
The History and Folklore of North American Wild Flowers
.
Houghton Mifflin Company Press
,
New York, USA
. pp.
235
247
.
4.
Srivastava
S
,
Singh
,
Adarsh Pratap.
,
Rawat
,
Ajay Kumar Singh
.
2012
.
A HPTLC method for the identification of ferulic acid from Lycopodiumclavatum. Asian Pacific
Journal of Tropical Biomedicine.
S12
S14
.
5.
Bureau of Fisheries and Aquatic Resources
,
1985
.
6.
Lalisan
,
J.
,
Nuñeza
,
O.M.
&
Uy
,
M.M.
(
2014
).
Brine shrimp (Artemia salina) bioassay of the medicinal plant Pseudelephantopus spicatus from Iligan City, Philippines
.
International Research Journal of Biological Sciences
,
3
(
9
):
47
50
.
7.
Kiranmai
,
M.
,
Mahendra
,
K.
&
Ibrahim
,
M.
(
2011
).
Comparison of total flavanoid content of Azadirachta indica root bark extracts prepared by different methods of extraction. Research Journal of Pharmaceutical
,
Biological and Chemical Sciences
,
2
(
3
):
254
265
.
8.
Aguinaldo
A.M.
,
Espeso
E.I.
,
Guevara
B.Q.
and
Nonato
M.G.
(
2005
). Phytochemistry. In:
Guevara
B.Q.
(ed.)
A Guidebook to Plant Screening: Phytochemical and Biological
.
University of Santo Tomas
,
Manila, Philippines
.
9.
Yusufoglu
HS
,
Alqasoumi
SI
. (
2011
).
Anti-inflammatory and Wound Healing Activities of Herbal Gel Containing an Antioxidant Tamarix aphylla Leaf Extract
.
Int J Pharmacol
:
7
:
829
835
.
10.
Bruneton
J.
(
1995
)
Pharmacognosy, Phytochemistry, Medicinal Plants
. (
Lavisior
,
Paris
).
11.
Cowan
,
MM
. (
1999
).
Plant Products as Antimicrobial Agents. Clin.Microbiol. Rev.
12
(
4
):
564
582
12.
Heinrich
,
M.
and
Gibbons
,
S.
(
2001
).
Ethnopharmacology In Drug Discovery: An Analysis Of Its Role And Potential Contribution
.
Journal of Pharmacy and Pharmacology.
53
:
425
432
.
13.
Gurib-Fakim
(
2006
).
Molecular Aspects of Medicine.
27
(
1
):
1
93
.
14.
Taiz
,
L.
and
Zeiger
,
E.
(
2002
).
Plant physiology
, 3rd edition, pp. 290,
294
300
,
Sinauer Associates, Inc.
23 Plumtree Road/PO Box 407, Sunderland Maryland 01375,
USA
.
15.
Moon
YJ
,
Wang
X
,
Morris
ME
. (
2006
).
Dietary flavonoids: Effects on xenobiotic and carcinogen metabolism. Toxicol
.
In vitro
20
:
187
210
.
16.
Veitch
NC
. (
2007
).
Isoflavonoids of the Leguminosae
.
Nat. Prod. Rep.
24
:
417
464
.
17.
Jiang
H
,
Zhan
WQ
,
Liu
X
,
Jiang
SX
. (
2008
).
Antioxidant activities of extracts and flavonoid compounds from Oxytropis falcate Bunge
.
Nat. Prod. Res.
22
(
18
):
1650
1656
.
18.
Kim
HP
,
Son
KH
,
Chang
HW
,
Kang
SS
. (
2004
).
Anti-inflammatory Plant Flavonoids and Cellular Action Mechanisms
.
J. Phamacol. Sci.
96:229
245
.
19.
Wu
JH
,
Tung
YT
,
Chien
SC
,
Wang
SY
,
Kuo
YH
,
Shyur
LF
,
Chang
ST
(
2008
).
Effect of Phytocompounds from the Heart-wood of Acaciaconfusa on Inflammatory Mediator Production
.
J. Agric. Food Chem.
56
:
1567
1573
.
20.
Blois
,
M.S.
(
1958
).
Antioxidant determinations by the use of a stable free radical
,
Nature
,
181
:
1199
1200
.
21.
Mandal
SK
,
Biswas
R
,
Bhattacharyya
SS
,
Paul
S
,
Dutta
S
,
Pathak
S
,
Khuda-Bukhsh
AR
. (
2010
).
Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation
.
European Journal of Pharmacology.
626
(
2-3
):
115
122
.
22.
Zhang
YJ
,
Gan
RY
,
Li
S
,
Zhou
Y
,
Li
AN
,
Xu
DP
,
Li
HB
. (
2015
).
Antioxidant phytochemicals for the prevention and treatment of chronic diseases
.
Molecules
20
(
12
):
21138
21156
.
This content is only available via PDF.
You do not currently have access to this content.