To perform a comparative analysis of osseointegration of bioceramic alumina-based granules, hydroxyapatite-based granules, and deproteinized bone granules. The experiment was conducted on 52 adult male Kyoto-Wistar rats weighing 350 to 520 g. The animals were divided into five matched groups that differed only in the type of an implanted material. The granules were implanted in the lumbar vertebral bodies and in the distal right femur of each laboratory animal. Two months after surgery, the animals were euthanized, followed by tissue sampling for morphological studies. An examination of specimens from the groups with implanted alumina granules revealed the newly formed trabecular bone with remodeling signs. The bone tissue filled the intragranular space, tightly adhering to the granule surface. There was no connective tissue capsule on the border between bone tissue and alumina granules. Cylindrical bioceramic alumina-based granules with an open internal channel have a higher strength surpassing than that of analogs and the osseointegration ability close to that of hydroxyapatite and deproteinized bone granules.
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2 August 2016
PHYSICS OF CANCER: INTERDISCIPLINARY PROBLEMS AND CLINICAL APPLICATIONS (PC’16): Proceedings of the International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016
22–25 March 2016
Tomsk, Russia
Research Article|
August 02 2016
Osseointegration of alumina bioceramic granules: A comparative experimental study Available to Purchase
V. V. Rerikh;
V. V. Rerikh
a)
1
Tsivyan Novosibirsk Research Institute of Traumatology and Orthopedics
, Novosibirsk, 630091 Russia
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A. R. Avetisyan;
A. R. Avetisyan
1
Tsivyan Novosibirsk Research Institute of Traumatology and Orthopedics
, Novosibirsk, 630091 Russia
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A. M. Zaydman;
A. M. Zaydman
1
Tsivyan Novosibirsk Research Institute of Traumatology and Orthopedics
, Novosibirsk, 630091 Russia
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K. A. Anikin;
K. A. Anikin
1
Tsivyan Novosibirsk Research Institute of Traumatology and Orthopedics
, Novosibirsk, 630091 Russia
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V. A. Bataev;
V. A. Bataev
2
Novosibirsk State Technical University
, Novosibirsk, Russia
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A. A. Nikulina;
A. A. Nikulina
2
Novosibirsk State Technical University
, Novosibirsk, Russia
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M. A. Sadovoy;
M. A. Sadovoy
1
Tsivyan Novosibirsk Research Institute of Traumatology and Orthopedics
, Novosibirsk, 630091 Russia
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A. M. Aronov;
A. M. Aronov
1
Tsivyan Novosibirsk Research Institute of Traumatology and Orthopedics
, Novosibirsk, 630091 Russia
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E. S. Semantsova
E. S. Semantsova
3
CJCS NEVZ Ceramics
, Novosibirsk, Russia
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V. V. Rerikh
1,a)
A. R. Avetisyan
1
A. M. Zaydman
1
K. A. Anikin
1
V. A. Bataev
2
A. A. Nikulina
2
M. A. Sadovoy
1
A. M. Aronov
1
E. S. Semantsova
3
1
Tsivyan Novosibirsk Research Institute of Traumatology and Orthopedics
, Novosibirsk, 630091 Russia
2
Novosibirsk State Technical University
, Novosibirsk, Russia
3
CJCS NEVZ Ceramics
, Novosibirsk, Russia
a)
Corresponding author: [email protected]
AIP Conf. Proc. 1760, 020055 (2016)
Citation
V. V. Rerikh, A. R. Avetisyan, A. M. Zaydman, K. A. Anikin, V. A. Bataev, A. A. Nikulina, M. A. Sadovoy, A. M. Aronov, E. S. Semantsova; Osseointegration of alumina bioceramic granules: A comparative experimental study. AIP Conf. Proc. 2 August 2016; 1760 (1): 020055. https://doi.org/10.1063/1.4960274
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