Goose grass also known as Eleusine indica (EI) is a local medicinal plant that displays antioxidant, antimicrobial and anticancer activities. The present study is to determine the phytochemical constituents, cytotoxicity and antiviral activities for both crude extract and fraction obtained from the plant. The crude extract contained more secondary metabolites compared to the hexane fraction as gauged using standard phytochemical tests. Cytotoxicity screening against Vero cells using MTT assay showed that the CC50 values for crude extract and hexane fraction were 2.07 and 5.62 mg/ml respectively. The antiviral activity towards Herpes Simplex Virus type 1 (HSV-1) was determined using plaque reduction assay. The selective indices (SI = CC50 / EC50) for both methanol extract and hexane fraction were 12.2 and 6.2 respectively. These results demonstrate that the extract prepared from E. indica possesses phytochemical compound that was non cytotoxic to the cell with potential antiviral activity.
Skip Nav Destination
Research Article| September 25 2015
Phytochemistry, cytotoxicity and antiviral activity of Eleusine indica (sambau)
Wan Ahmad Yaacob;
AIP Conf. Proc. 1678, 030013 (2015)
Rashidah Iberahim, Wan Ahmad Yaacob, Nazlina Ibrahim; Phytochemistry, cytotoxicity and antiviral activity of Eleusine indica (sambau). AIP Conf. Proc. 25 September 2015; 1678 (1): 030013. https://doi.org/10.1063/1.4931234
Download citation file: