Effect of increase in intraperitoneal pressure on fluid distribution in tissue using finite difference method

In this study, peritoneal dialysis transport system was numerically simulated using finite difference method. The increase in the intraperitoneal pressure due to coughing has a high value outside the working area of the void volume fraction of the hydrostatic pressure θ(P). Therefore to illustrate the effects of the pressure increment, the pressure of working area is chosen between 1 and 3 mmHg. The effects of increased pressure in peritoneal tissue cause more fluid to flow into the blood vessels and lymph. Furthermore, the increased pressure in peritoneal tissue makes the volumetric flux j_v and solute flux j_s across the tissue also increase. The more fluid flow into the blood vessels and lymph causes the fluid to flow into tissue q_v and the glucose flow q_s to have more negative value and also decreases the glucose concentration C_G in the tissue.