Synthesis of Zn or CO32− substituted nano‐hydroxyapatite (HA) and its physico‐chemical properties have been well documented. However, the effects of the simultaneous substitution of Zn and CO32− in nano‐HA have not been reported. In the present study, Zn and CO32− substitutions in nano HA independently and concurrently have been done by wet precipitation method and characterized by XRD and FT‐IR for its phase purity and chemical homogeneity. Further modulations of the bioactivity and thermal stability of HA due to the substitutions have been studied.

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