Light therapy commonly referred to as low level laser therapy can alter cellular functions and clinical conditions. Some of the commonly reported in vitro and in vivo effects of light therapy include cellular proliferation, alterations in the inflammatory response to injury, and increases in mitochondrial respiration and adenosine triphosphate synthesis. Based on the known effects of light on cells and tissues in general and on reports in the last 5 years on the interaction of light with stem cells, evidence is mounting indicating that light therapy could greatly benefit stem cell regenerative medicine. Experiments on a variety of harvested adult stem cells demonstrate that light therapy enhances differentiation and proliferation of the cells and alters the expression of growth factors in a number of different types of adult stem cells and progenitors in vitro. It also has the potential to attenuate cytotoxic effects of drugs used to purge harvested autologous stem cells and to increase survival of transplanted cells.
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31 May 2010
LASER FLORENCE 2009: A Gallery Through the Laser Medicine World
6–7 November 2009
Firenze (Italy)
Research Article|
May 31 2010
The Combination of Light and Stem Cell Therapies: A Novel Approach in Regenerative Medicine Available to Purchase
Juanita Anders;
Juanita Anders
aDepartment of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814 USA
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Helina Moges;
Helina Moges
aDepartment of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814 USA
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Xingjia Wu;
Xingjia Wu
aDepartment of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814 USA
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Ilko Ilev;
Ilko Ilev
bCenter for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD 20993 USA
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Ronald Waynant;
Ronald Waynant
bCenter for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD 20993 USA
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Leonardo Longo
Leonardo Longo
cInstitute of Laser Medicine, University of Siena, Siena 53100, Italy and University of San Marino 47890, San Marino Republic
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Juanita Anders
a
Helina Moges
a
Xingjia Wu
a
Ilko Ilev
b
Ronald Waynant
b
Leonardo Longo
c
aDepartment of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814 USA
bCenter for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD 20993 USA
cInstitute of Laser Medicine, University of Siena, Siena 53100, Italy and University of San Marino 47890, San Marino Republic
AIP Conf. Proc. 1226, 3–10 (2010)
Citation
Juanita Anders, Helina Moges, Xingjia Wu, Ilko Ilev, Ronald Waynant, Leonardo Longo; The Combination of Light and Stem Cell Therapies: A Novel Approach in Regenerative Medicine. AIP Conf. Proc. 31 May 2010; 1226 (1): 3–10. https://doi.org/10.1063/1.3453785
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