Knuckle pads are common skin lesions not disease associated and seen as thickended skin like nodules situated usually on the dorsal site of the proximal interphalangeal joints. Neither medical nor surgical procedures are very effective to remove knuckle pads. A women 22 years of age with knuckle pads on the fingers two and three on both hands which reoccurred after surgical resections was successful treated with a long pulsed Erbium:YAG laser. All four fingers were ablated within one single treatment. The aesthetic result was excellent and lasted at least for 18 months.

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