We present a novel integrated methodology for the development and production of accessible physics and science books from the elementary up to tertiary educational levels. This language independent approach adopts the Design‐for‐All principles, the available international standards for alternative formats and the Universal Design for Learning (UDL) Guidelines. Moreover it supports both static (embossed and refreshable tactile) and dynamic (based on synthetic speech and other sounds) accessibility. It can produce Tactile Books (Embossed Braille and Tactile Graphics), Digital Talking Books (or Digital Audio Books), Large Print Books as well as Acoustic‐Tactile Books for the blind and visually impaired students as well as but for the print‐disabled. This methodology has been successfully applied in the case of blind students of the Physics, Mathematics and Informatics Departments in the University of Athens.

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