The next generation of radiobiology research requires increasingly more complex radiation sources to address questions ranging from the effects of space‐based radiation to the influence of dose rate on biological systems. The Idaho Accelerator Center (IAC) has developed a radiobiology research facility to address some of these questions. The irradiation challenge is to deliver stable and reproducible conditions of high dose rate with well‐controlled beam uniformity, dose, and dose rate under controlled temperature. In this work, we used a 25 MeV modified medical grade linear accelerator (LINAC) to obtain a high and adjustable electron dose rate. To overcome electron beam drift we used a collimator that both assisted the LINAC operator to steer the beam and ensured that regardless of beam drift, only the fixed collimated beam would irradiate the specimens. In addition, we utilized a beam flattener to keep the beam variation as low as 3% at 2.5 cm from the beam’s center, and 1% variation between the simultaneously irradiated sample tubes. We also demonstrated that a segmented Faraday “cup” (FC) array provides a useful real‐time beam scanning and monitoring system, and is promising for implementing real‐time dosimetry and control.
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10 March 2009
APPLICATION OF ACCELERATORS IN RESEARCH AND INDUSTRY: Twentieth International Conference
10–15 August 2008
Fort Worth (Texas)
Research Article|
March 10 2009
Real‐Time Dosimetry for Radiobiology Experiments Using 25 MeV LINAC
Mohammed A. Mestari;
Mohammed A. Mestari
cDepartment of Physics, Idaho State University, 921 S. 8th St., MS 8106, Pocatello, ID 83209
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Douglas P. Wells;
Douglas P. Wells
aIdaho Accelerator Center, Idaho State University, 921 S. 8th St., MS 8263, Pocatello, ID 83209
cDepartment of Physics, Idaho State University, 921 S. 8th St., MS 8106, Pocatello, ID 83209
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Linda C. DeVeaux;
Linda C. DeVeaux
aIdaho Accelerator Center, Idaho State University, 921 S. 8th St., MS 8263, Pocatello, ID 83209
bDepartment of Biological Sciences, Idaho State University, 921 S. 8th St., MS 8007, Pocatello, ID 83209
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Alan Hunt;
Alan Hunt
aIdaho Accelerator Center, Idaho State University, 921 S. 8th St., MS 8263, Pocatello, ID 83209
cDepartment of Physics, Idaho State University, 921 S. 8th St., MS 8106, Pocatello, ID 83209
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Syed F. Naeem
Syed F. Naeem
cDepartment of Physics, Idaho State University, 921 S. 8th St., MS 8106, Pocatello, ID 83209
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AIP Conf. Proc. 1099, 3–6 (2009)
Citation
Mohammed A. Mestari, Douglas P. Wells, Linda C. DeVeaux, Alan Hunt, Syed F. Naeem; Real‐Time Dosimetry for Radiobiology Experiments Using 25 MeV LINAC. AIP Conf. Proc. 10 March 2009; 1099 (1): 3–6. https://doi.org/10.1063/1.3120062
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