We present the outline of a new course designed to teach the physical principles underlying biological measurements. This course, intended for undergraduate and first‐year graduate students who have taken noncalculus introductory physics, is primarily aimed at biological science and biophysics majors interested in research careers in those fields. The course consists of lectures and demonstrations on a series of topics including NMR, ultracentrifugation, electronics, and optical and electron microscopy. Our intent is to teach the student the principles underlying the measurements they perform in their laboratories and the uses and limitations of the various techniques.

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